PROJECT   ABSTRACT

 

Project Name :  the Experiment and Research on Chinese Herbal Medicine With Anti-thrombotic Effects and Decreasing R.B.C. Aggregatibility

 

Main Complete Unit:  the First Affililiated Hospital of JiangXi Medical College

                    Jiangxi Chinese Medicine Academy

Project Brief Introduction :

 

The project was subsidized by National Natural Science Fund . According to Chinese medical theory of promoting blood circulation to dissipate blood stasis and the theory of Hemoreology , we have selected 7 types and 575 kinds of Chinese herbal medicines and 122 complex prescriptions, which have the effects of promoting blood circulation to dissipate blood stasis. Then the basic and clinic experiments and research on Chinese Herbal Medicine With Anti-thrombotic Effects and Dereasing R.B.C. Aggregatibility were carried out, which are systemic , profound , integrated and large-samples. The project has revealed 219 kinds and 67 complex prescriptions with anti-thrombotic effects, 124 kinds and 52 complex prescriptions with thrombolytic effects and 12 kinds of drugs and 4 complex prescriptions which are better at decreasing RBC aggregatibility than low molecular dextran(P<0.05-0.001). Authors have initiated A Reference Table of Intensity of Chinese Herbal Medicines with Thrombolytic Effects and A Reference Table of Intensity of Chinese Herbal Medicines with Anti-thrombotic Effects and presented new access and clue to develop natural medicines with the effects of anti-thrombosis and thrombolytic. They have initiated a new experimental method , Hematological Model of Natural Blood Stasis Syndrome, initiated new theory , Hypothesis on Blood Viscosity Syndrome . In the same time, clinical research was carried out to prove the hypothesis . Large number of articles have been published by the national and international publish companies and magazines, one of which is collected by American medical Index , 8 of which are reprinted by authoritative international magazines, 10 of which are collected by CD database( one by American Medical Index and nine by Chinese Biologic Medicine) , one of which is selected by European Medical Science Annals , three of which are selected by Hand-picked Article of Chinese Medical Research ,etc. Many famous experts in China and foreign countries have given the research a high praise ,such as the founder of international biocreology , American professor Yang-Cheng Fang , etc, on  Academic communication conference of the ninth international biocreology and second international clinical hemorheology in 1995, Chinese 96` blood stasis syndrome, thrombotic-diseases and anti-thrombotic enzyme academic seminar , and new development seminar of Chinese clinical medicine.

The research is an significant achievement of integrated western and Chinese traditional medicine, Which has creative, advanced, scientific and practicable quality . It is important progress in the field of science and has notable value on speeding up the development of integrated traditional Chinese and western medicine, Chinese medical theory of promoting blood circulation to dissipate blood stasis and the theory of Hemoreology.  The achievement is advanced in the academic field of our country and the world . Three academicians in Chinese academy of Science and Chinese academy of engineering have paid high appraise to the achievement and recommended it to contest Chinese Medical Technological Award.